Vitamin D Fights Crohn’s Disease

Mercola.com February 20 2010

Dr Mercola

A new study has found that Vitamin D can counter the effects of Crohn’s disease.

Researchers found that Vitamin D acts directly on the beta defensin 2 gene, which encodes an antimicrobial peptide, and the NOD2 gene that alerts cells to the presence of invading microbes.

Both beta defensin and NOD2 have been linked to Crohn’s disease. If NOD2 is deficient or defective, it cannot combat invaders in the intestinal tract.

Sources:
Eurekalert January 27, 2010

For more go here.

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One Response to Vitamin D Fights Crohn’s Disease

  1. The problem with oral Vitamin D supplementation for people with chronic inflammation and weakness of the gastrointestinal tract, is poor absorption of D3 from foods and supplements.
    While regular 20~30 minutes non burning, full body, sun (UVB) exposure may provide an effective source of Vitamin D3 for those with sufficient cholesterol in skin to convert we have to be realistic. In urban situations, although UV exposure is greater (bounced of windows, walls, roads), atmospheric pollution absorbs/blocks UVB so urban folk get more UVA (damages skin and degrades D3) than UVB, so they MAY NOT make effective amounts of vitamin D3.
    Regular 25(OH)D testing is the only way to be certain sun exposure is working for you. Above latitude 42 little or NO vitamin D is made between October and March so apart from those with access to a UVB sunbed supplements are the only source of effective amounts of D3.
    1000iu/daily/D3 per 25lbs or pro rata. 100iu per 2.5lbs from 1 month old.
    But for those with damaged intestines consider a sublingual spray so absorption takes place under the tongue.
    Another possiblity is 5000iu MCT oil based D3 capsules. MCT oil is very stable so doesn’t go rancid, capsules could be chewed and the contents held in the mouth until absorbed either sublingually or through skin.
    They may also want to try piercing the capsule and squirting the contents onto skin surface (ideally somewhere UVA won’t degrade it) and massage it into the skin. MCT is very quickly absorbed and metabolised so the D3 is less likely to be transported for storage.
    There is interesting new research showing curcumin (turmeric) acts as a Vitamin D Receptor ligand (triggers them to act) so Crohns patients may want to increase the amount of turmeric they consume as well although of course spicy foods may be off limits for many.

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